transporteurs anions organiques

    H patotoxicit - PharmaEtudes- transporteurs anions organiques ,Pole sinuso dale cation organique conjugu s Transporteurs anions organiques conjugu s Ac biliaire :taurocholate, Anion organique Cation organique Compos s absorb s au niveau canalicule Compos s h patotoxiques : tr s nombreux,.transporteurs d'anions organiques - CHU de RouenLibell pr f r : transporteurs d'anions organiques; Synonyme CISMeF : transporteurs anions organiques; Transport anions organiques, prot ines; Prot ines de transport anions organiques; prot ines de transport d'anions organiques;.



  • Interactions of rifamycin SV and rifampicin with organic anion uptake ,

    In rats, rifamycin SV and rifampicin were shown to interfere with hepatic organic anion uptake by inhibition of the organic , In conclusion, these results show that rifamycin SV and rifampicin interact with OATP-mediated substrate transpo.

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  • Renal secretion of organic anions and cations

    Renal secretion of organic anions and cations The renal proximal tubule actively transports charged, potentially toxic xenobiotics from blood to lumen Basolateral uptake of organic anions is indirectly coupled to the sodium gradient throu.

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  • Characterization of methotrexate transport and its drug interactions ,

    J Pharmacol Exp Ther 2002 Aug;302(2):666-71 Characterization of methotrexate transport and its drug interactions with human organic anion transporters Takeda M(1), Khamdang S, Narikawa S, Kimura H, Hosoyamada M, Cha SH, Sekine,.

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  • Interactions of the human multidrug resistance proteins MRP1 and ,

    The human multidrug resistance protein MRP1 and its homolog, MRP2, are both suggested as being involved in cancer drug resistance and the transport of organic anions We expressed MRP1 and MRP2 in Spodoptera frugiperda ovarian,.

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  • OAT3 - Transporters | Solvo Biotechnology

    SLC22A8, more commonly referred to as OAT3 (Organic Anion Transporter 3), is a renal uptake transporter that plays a key role , OAT3 is also able to transport, albeit with low affinities, the cationic drugs cimetidine, famotidine and rani.

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  • transporteurs d'anions organiques - CHU de Rouen

    Libell pr f r : transporteurs d'anions organiques; Synonyme CISMeF : transporteurs anions organiques; Transport anions organiques, prot ines; Prot ines de transport anions organiques; prot ines de transport d'anions organiques;.

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  • Organic Anion Transporter 3 (Oat3/Slc22a8) Interacts with ,

    Basolateral uptake of carboxyfluoroquinolones seems to involve an organic anion transport mechanism, because levofloxacin inhibited basolateral p-aminohippurate uptake into opossum kidney cells (Matsuo et al, 2001), and basal uptake of.

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  • Transports membranaires Bioenergetique Enseignement et ,

    transport membrane membranaire actif passif diffusion osmose pompe gradient potentiel potential electrique , les acides amin s et les peptides, les osmolites, les siderophores, les nucl osides, les anions organiques et inorganiques ,.

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  • Drug transport by Organic Anion Transporters (OATs) - ScienceDirect

    25 Jul 2012 , Abstract Common to all so far functionally characterized Organic Anion Transporters (OATs) is their broad substrate specificity and their ability to exchange extracellular against intracellular organic anions Many OATs occ.

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  • ministere de la jeunesse, de l'education nationale - EPHE

    Les transporteurs h patiques jouent un r le majeur dans l' limination biliaire des x nobiotiques et interviennent par cons quent dans , d' limination des anions organiques au p le biliaire, l'expression du transporteur MRP3.

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  • Renal secretion of organic anions and cations

    Renal secretion of organic anions and cations The renal proximal tubule actively transports charged, potentially toxic xenobiotics from blood to lumen Basolateral uptake of organic anions is indirectly coupled to the sodium gradient throu.

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  • Renal Excretion and Tubular Transport of Organic Anions and ,

    Other factors influencing organic anion secretion Comparative physiology of organic anion secretion Mechanisms involved in tubular transport of organic anions Methodological aspects Transport across basolateral membran ANIMALS,.

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  • Drug transport by Organic Anion Transporters (OATs) - ScienceDirect

    25 Jul 2012 , Abstract Common to all so far functionally characterized Organic Anion Transporters (OATs) is their broad substrate specificity and their ability to exchange extracellular against intracellular organic anions Many OATs occ.

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  • Interactions of human organic anion transporters and human ,

    The purpose of this study was to elucidate the interactions of human organic anion transporters (hOATs) and human , hOATs and hOCTs interacted with various NSAIDs, whereas hOATs but not hOCTs mediated the transport of some of these,.

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  • Transports r naux de m dicaments : m canismes et potentiel d ,

    R sum Les syst mes de s cr tion tubulaire active d'anions et de cations organiques jouent un r le important dans l'excr tion r nale de certains m dicaments De nombreux transporteurs ont t identifi s et caract ris s dans les cel.

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  • Goutte - Service de Rhumatologie

    16 mai 2011 , Plusieurs g nes codant pour des transporteurs tubulaires d'acide urique sont impliqu s dans l'hyperuric mie et donc dans la , MRP4 et un transporteur organique d'anions voltage-d pendant (vOAT1/NPT1) sont can.

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  • Audrey MURAT_RINGOT - EPHE

    des inhibiteurs pour diff rents transporteurs d'anions organiques, nous avons tent de caract riser les transporteurs , pourrait tre un membre de la famille des oatp (organic anion transport protein), mais ne permettent pas de conclu.

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  • The superfamily of organic anion transporting polypeptid

    Organic anion transporting polypeptides (Oatps/OATPs) form a growing gene superfamily and mediate transport of a wide spectrum of amphipathic organic solut Different Oatps/OATPs have partially overlapping and partially distinct,.

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  • SLCO1B3 - Solute carrier organic anion transporter family member ,

    Mediates the Na(+)-independent uptake of organic anions such as 17-beta-glucuronosyl estradiol, taurocholate, triiodothyronine , small molecule metabolic process Source: Reactome; sodium-independent organic anion transport Source:,.

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  • Impact of OATP transporters on pharmacokinetics

    28 Sep 2009 , Organic anion transporting polypeptides (OATP) form a family of influx transporters expressed in various tissues , Val174Ala) in the SLCO1B1 gene encoding OATP1B1 decreases the ability of OATP1B1 to transport active,.

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  • Transport of the natural sweetener stevioside and its aglycone ,

    J Pharmacol Exp Ther 2005 May;313(2):621-8 Epub 2005 Jan 11 Transport of the natural sweetener stevioside and its aglycone steviol by human organic anion transporter (hOAT1; SLC22A6) and hOAT3 (SLC22A8) Srimaroeng C(1),.

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  • Organic Anion Transporters and Their Implications in ,

    Localization, Substrate Specificity and Molecular Pharmacology of Organic Anion Transporter Family Members; A Organic Anion Transporter 1 , These studies indicated that this protein was capable of mediating transport of organic anions,.

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  • Cholestase, lithiase et g n tique, - Soci t Royale Belge de ,

    capacit s de liaison et de transport La liste des transporteurs responsables identifi s au niveau de la membrane h patocytaire sinuso dale s'allonge r guli rement (transporteurs du taurocholate, des anions organiques, des cations.

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  • Effet d'un traitement par extraits de soja - AVK Control

    Mots-cl s : fluindione, isoflavones, interaction, glycoproteine P, polypeptides transporteurs d'anions organiqu Introduction L'une des premi res causes d'iatrog nie m dicamenteuse conduisant une hospitalisation est constit.

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  • OATPs, OATs and OCTs: the organic anion and cation transporters ,

    Substrates of OATPs are mainly large hydrophobic organic anions, while OATs transport smaller and more hydrophilic organic anions and OCTs transport organic cations In addition to endogenous substrates, such as steroids, hormones and.

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  • doc file 47Ko - Soci t Royale Belge de Gastro-Ent rologie

    La liste des transporteurs responsables identifi s au niveau de la membrane h patocytaire sinuso dale s'allonge r guli rement (transporteurs du taurocholate, des anions organiques, des cations organiques, des prostaglandines, des acid.

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  • Evaluation of the effect of cobicistat on the in vitro renal transport ,

    29 Jul 2013 , Evaluation of the effect of cobicistat on the in vitro renal transport and cytotoxicity potential of tenofovir , Male; Multidrug Resistance-Associated Proteins/metabolism; Organic Anion Transport Protein 1/metabolism; Org.

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  • S cr tion biliaire - John Libbey Eurotext

    Mots-cl s : s cr tion biliaire, transport h patocytaire, acides biliaires, anions organiques, cholestases g n tiqu , La s cr tion biliaire limine les anions organiques endog nes (acides biliaires, bilirubine) et exog nes (x nobiotique.

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  • Propri t s de transport de membranes changeuses d'anions en ,

    Abstract Transport properties of anion exchange membranes in contact with organic ions Part I Influence of the length of the aliphatic chain The physico-chemical properties of an anion-exchange membrane (AMV, Asahi Glass) were studied.

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  • Roles of organic anion transporters (OATs) and a urate transporter ,

    Roles of organic anion transporters (OATs) and a urate transporter (URAT1) in the pathophysiology of human disease , distal tubules are highly polarized epithelial cells that carry out the specialized directional transport of various sol.

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  • The multispecific organic anion transporter (OAT) family

    Organic anion transporters play important roles in the elimination of a variety of endogenous substances, xenobiotics and their , Animals; Anion Transport Proteins; Carrier Proteins*/chemistry; Carrier Proteins*/genetics; Carrier Proteins.

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  • Heat stress enhances recovery of hepatocyte bile acid and organic ,

    Without HS, endotoxins have been shown to induce a transcriptional down-regulation of hepatocyte transport proteins for bile acids and organic anions We performed experiments in isolated perfused rat livers at various times after LPS.

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  • Organic anion transporter 3 (oat3/slc22a8) interacts with ,

    1 Apr 2008 , Organic anion transporter 3 (oat3/slc22a8) interacts with carboxyfluoroquinolones, and deletion increases , norfloxacin, ofloxacin, and gatifloxacin exhibited concentration-dependent inhibition of transport on mOat3 in cell.

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  • Propri t s de transport de membranes changeuses d'anions en ,

    Abstract Transport properties of anion exchange membranes in contact with organic ions Part I Influence of the length of the aliphatic chain The physico-chemical properties of an anion-exchange membrane (AMV, Asahi Glass) were studied.

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  • Characterization of methotrexate transport and its drug interactions ,

    J Pharmacol Exp Ther 2002 Aug;302(2):666-71 Characterization of methotrexate transport and its drug interactions with human organic anion transporters Takeda M(1), Khamdang S, Narikawa S, Kimura H, Hosoyamada M, Cha SH, Sekine,.

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  • R daction th se DERNIERE VERSION - Universit de Franche-Comt

    passive diffusion, an Oatp2 stationary phase (Organic anion transporting polypeptide 2) and cell membrane stationary phases (CMSP) , OATPs : Organic Anion Transporting Polypeptides ou transporteurs polypeptides d'anions organiqu.

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  • MEMOIRE de MAGISTER - Universit Mouloud Mammeri de Tizi ,

    qu'elle nous a apport e en nous fournissant l'extractant transporteur TBP qui m'a permis de r aliser ce travail Je remercie vivement ,, entre un cation et un anion plus ou moins troitement associ s dans la phase organique,.

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  • FYCOMPA 2 mg cp pellic - pharmacocinetique - Vidalfr

    20 f vr 2015 , Des tudes in vitro montrent que le p rampanel n'est pas un substrat ni un inhibiteur significatif des polypeptides transporteurs d'anions organiques (OATP) 1B1 et 1B3, des transporteurs d'anions organiques (OA.

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  • Organic Anion Transporting Polypeptide 1B1: a Genetically ,

    Organic anion transporting polypeptide 1B1 (OATP1B1) is a genetically polymorphic influx transporter expressed on the , The mechanism of its substrate transport is not completely understood, although it has been suggested that OATPs.

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  • Organic Anion Transporters and Their Implications in ,

    Localization, Substrate Specificity and Molecular Pharmacology of Organic Anion Transporter Family Members; A Organic Anion Transporter 1 , These studies indicated that this protein was capable of mediating transport of organic anions,.

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